STORY

Microbiome

Various treatments using animal venom

Various treatments using animal venom

After being bitten by a spider in a lab, he gains spider powers. This
is a setting from Spider-Man. Many children have probably thought that if they were bitten by a spider, they would become Spider-Man.

The idea that poison can be medicine is not just an imagination, and in many cases, poison is used as a treatment.
Exposure to the venom of the funnel-web spider in the rainforests of southern Queensland can cause rapid heartbeat, difficulty breathing, and even death, but the peptide contained in this venom can also prevent the spread of melanoma.
Venom components found in various animals are also being studied as potential therapeutic agents for various diseases. Some conotoxins have a nerve-paralyzing poison called conotoxin, and the painkiller ziconitide, approved by the US Food and Drug Administration in 2004, is one of these conotoxins and is a peptide made of 25 amino acids. This ziconitide is said to be effective in relieving severe pain that does not respond to morphine painkillers.
Technology is gradually developing to purify only the beneficial components from the venom of various animals and use them as medicine.

We have moved from the era of using animal poisons to the era of the microbiome, and now we have entered the era of using bacterial poisons.
The most representative example is the ‘Botox’ injection.
Botulinum toxin is a biological toxic protein extracted from Clostridium botulinum.
The bacteria itself is very common and has no toxicity of its own, but it germinates in anaerobic conditions without oxygen and secretes toxins outside the body. The toxin ‘Botox’ produced by this bacteria, which mainly lives in fish, is one of the most toxic substances among all toxins discovered or developed by mankind to date. The
mass required for Botox to kill an adult male is only 0.5ng/kg. The lethal dose of cyanide, which can kill by simply wiping your nose or mouth with a powdered hand, is 0.15g, the tetrodotoxin, a poison of pufferfish, is 300-500ug, and polonium, known as an ingredient in radioactive black tea, is approximately 10ug, so it is impossible to even guess how strong botulinum toxin is. Just 1ml could kill thousands of people, and just 0.4kg could theoretically poison the entire human race.

Surprisingly, medicine uses the toxicity of this botox for cosmetic purposes. Although it is said that it uses a relatively weak toxin, type A toxin, it must be handled with great care because it is a deadly poison itself. The toxicity of botox is used to improve external appearance by locally paralyzing the muscles of a specific area, or to treat various diseases caused by hypertrophied muscles.
Some people foolishly inject botox into their lips, which have many microvessels, to make their lips plump. This is a dangerous act that can lead to death.

Many companies and research institutes are studying various microbiomes and looking for new drugs like the case of Botox. It’s like finding treasure in a garbage dump…
After various attempts and trial and error, another groundbreaking drug can be found from the secretion of microorganisms.
AI Biotics is also looking for this. Thousands of clinical data and gut microbiome analysis data are still insufficient to find definitive evidence, but as more data accumulates, the identity of the trap set in advance will be revealed.

#spiderman #spider #botox #cyanide #tetrodotoxin #radioactivetea #botulinum #toxicprotein #intestinalmicrobes #smileempathy #Aibiotics

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